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Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes

2020-03-11

Abstract excerpt

The three-dimensional organization of the genome supports regulated gene expression, recombination, DNA repair, and chromosome segregation during mitosis. Chromosome conformation capture (Hi-C) 1–3 has revealed a complex genomic landscape of internal chromosome structures in vertebrate cells 4–11 yet how sister chromatids topologically interact in replicated chromosomes has remained elusive due to their identica...

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Literature Corpus work
e37cf776-525a-5cab-b4ed-6775cba3beb4
DOI
10.1101/2020.03.10.978148
Open publication

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Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomesDOI 10.1101/2020.03.10.978148
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