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Article

Novel insights into chromosomal conformations in cancer.

Molecular cancer - 17 Nov 2017

Jia Ruobing, Chai Peiwei, Zhang He, Fan Xianqun

Abstract excerpt

Exploring gene function is critical for understanding the complexity of life. DNA sequences and the three-dimensional organization of chromatin (chromosomal interactions) are considered enigmatic factors underlying gene function, and interactions between two distant fragments can regulate transactivation activity via mediator proteins. Thus, a series of chromosome conformation capture techniques have been...

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Share to Nucleic Acid Conformation
Share to Chromatin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human

Share to Gene Expression Regulation, Neoplastic

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Identifiers

PMID: 29149895
DOI: 10.1186/s12943-017-0741-5
PMCID: PMC5693495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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