Article

Spatial transcriptomic analysis of HIV and tuberculosis coinfection in a humanized mouse model reveals unique transcription patterns, immune responses and early morphological alterations

2025-01-30

Abstract excerpt

Mycobacterium tuberculosis ( Mtb ) and human immunodeficiency virus (HIV) coinfection is one of the biggest public health concerns worldwide. Both pathogens are adept at modulating immune response and, in the case of Mtb , even inducing structural modification of the affected tissue. The present study aimed at understanding the early phenotypical and functional changes in immune cell infiltration in the affected...

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Literature Corpus work: e36823f2-d138-5c16-9dc0-5689fba4bb65
DOI: 10.1101/2025.01.29.635571

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