Article

Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response

2023-11-17

Abstract excerpt

<h4>ABSTRACT</h4> Postmortem single-cell studies have transformed understanding of lower respiratory tract diseases (LRTD) including Covid19 but there is almost no data from African settings where HIV, malaria and other environmental exposures may affect disease pathobiology and treatment targets. We used histology and high-dimensional imaging to characterise fatal lung disease in Malawian adults with (n=9) and w...

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Literature Corpus work: 2f4b8a65-cb7b-59ab-b97d-b4e29c6bc573
DOI: 10.1101/2023.11.16.566964

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