Article

Single-Cell and Spatial Transcriptomic Analyses Deciphering the Three-Layer Architecture of Human Tuberculosis Granulomas

2024-07-15

Abstract excerpt

<h4>Background</h4> Granulomas (defining tuberculosis histopathological feature) are central to the host’s defense against Mycobacterium tuberculosis , critically influencing patient outcomes. However, knowledge of human granulomas’ structure and function are incomplete. This study employs single-cell and spatial transcriptomics to dissect human granuloma’s cellular composition, structure, communication and func...

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Literature Corpus work: caee7f5a-263b-595e-9830-975957348a77
DOI: 10.1101/2024.07.15.603490

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