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CD8 <sup>+</sup> T cells mediate vaccination-induced lymphatic containment of latent <i>Mycobacterium tuberculosis</i> infection following immunosuppression, while B cells are dispensable

2025-01-24

Abstract excerpt

It is estimated that two billion people are latently infected with Mycobacterium tuberculosis ( Mtb ), the causative agent of tuberculosis (TB). Latent Mtb infection (LTBI) can occur in multiple organs, including the lymphatics. The risk of LTBI reactivation increases in immunocompromised conditions, such as coinfection with human immunodeficiency virus (HIV), and during treatment of autoimmune diseases and org...

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Literature Corpus work
3e2a0385-8663-575d-b968-fff93b9468df
DOI
10.1101/2025.01.23.634479
Open publication

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CD8 <sup>+</sup> T cells mediate vaccination-induced lymphatic containment of latent <i>Mycobacterium tuberculosis</i> infection following immunosuppression, while B cells are dispensableDOI 10.1101/2025.01.23.634479
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