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Shared and distinct responses of human and murine alveolar macrophages and monocyte-derived macrophages to <i>Mycobacterium tuberculosis</i>

2025-03-05

Abstract excerpt

<h4>ABSTRACT</h4> Macrophages serve as important sites of bacterial replication and host immune response during Mycobacterium tuberculosis (Mtb) infection with distinct roles for alveolar macrophages (AMs) early in infection and monocyte-derived (MDMs) during later stages of disease. Here, we leverage data from human and mouse models to perform a cross-species analysis of macrophage responses to Mtb infection. O...

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Literature Corpus work
9a904813-e12b-557e-a804-7123cd9619df
DOI
10.1101/2025.02.28.640814
Open publication

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Shared and distinct responses of human and murine alveolar macrophages and monocyte-derived macrophages to <i>Mycobacterium tuberculosis</i>DOI 10.1101/2025.02.28.640814
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