Article

PoreMeth2: decoding the evolution of methylome alterations with Nanopore sequencing

2024-10-03

Abstract excerpt

In epigenetic analysis, identifying differentially methylated regions (DMRs) typically involves detecting groups of consecutive CpGs that show significant changes in their average methylation levels. However, the methylation state of a genomic region can also be characterized by a mixture of patterns (epialleles) with variable frequencies, and the relative proportions of such patterns can provide insights into its...

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Literature Corpus work: e334e1ff-a829-5dff-8189-3c20fab8d1c4
DOI: 10.1101/2024.10.03.616449

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