Article

Genome-Wide Detection of Imprinted Differentially Methylated Regions Using Nanopore Sequencing

2021-07-18

Abstract excerpt

Imprinting is a critical part of normal embryonic development in mammals, controlled by defined parent-of-origin (PofO) differentially methylated regions (DMRs) known as imprinting control regions. As we and others have shown, direct nanopore sequencing of DNA provides a mean to detect allelic methylation and to overcome the drawbacks of methylation array and short-read technologies. Here we leverage publicly-avai...

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Literature Corpus work: 1c31a31d-43af-5b2c-8ddc-de361fd6e97b
DOI: 10.1101/2021.07.17.452734

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