Article

Population Performance and Individual Agreement of Coronary Artery Disease Polygenic Risk Scores

2024-07-26

Abstract excerpt

<h4>Importance</h4> Polygenic risk scores (PRSs) for coronary artery disease (CAD) are a growing clinical and commercial reality. Whether existing scores provide similar individual-level assessments of disease liability is a critical consideration for clinical implementation that remains uncharacterized. <h4>Objective</h4> Characterize the reliability of CAD PRSs that perform equivalently at the population level a...

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Literature Corpus work: e2f9e399-1dfc-5930-9628-197bbe9292c9
DOI: 10.1101/2024.07.25.24310931

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