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Article

Clinical utility of polygenic risk scores for coronary artery disease.

Nature reviews. Cardiology - 1 May 2022

Klarin Derek, Natarajan Pradeep

Abstract excerpt

Over the past decade, substantial progress has been made in the discovery of alleles contributing to the risk of coronary artery disease. In addition to providing causal insights into disease, these endeavours have yielded and enabled the refinement of polygenic risk scores. These scores can be used to predict incident coronary artery disease in multiple cohorts and indicate the clinical response to some...

Topics

Coronary Artery Disease
Genetic Predisposition to Disease
Humans
Multifactorial Inheritance
Prospective Studies
Risk Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34811547
DOI: 10.1038/s41569-021-00638-w
PMCID: PMC10150334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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