Article
Armed and Ready: Transcriptional Regulation of Tissue-Resident Memory CD8 T Cells.
Frontiers in immunology - 1 Jan 2018
Behr Felix M, Chuwonpad Ammarina, Stark Regina, van Gisbergen Klaas P J M
Abstract excerpt
A fundamental benefit of immunological memory is the ability to respond in an enhanced manner upon secondary encounter with the same pathogen. Tissue-resident memory CD8 T (TRM) cells contribute to improved protection against reinfection through the generation of immediate effector responses at the site of pathogen entry. Key to the potential of TRM cells to develop rapid recall responses is their location within...
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