Article

Klotho attenuates glucocorticoid-induced osteoblast cytotoxicity via Wnt signaling pathway modulation

2025-04-28

Abstract excerpt

<title>Abstract</title> <p>Background Glucocorticoids are commonly prescribed in clinical settings; however, their prolonged use at high doses can adversely affect human health. One significant complication following glucocorticoid therapy is glucocorticoid-induced osteoporosis (GIO), which is second in incidence only to senile osteoporosis. Objective Based on previous research indicating that Klotho alleviates...

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Literature Corpus work: e2653b4f-87a8-5431-9fd8-c56adf59110d
DOI: 10.21203/rs.3.rs-5854318/v1

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