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Sec-O-glucosylhamaudol Inhibits RANKL-induced Osteoclastogenesis Via Repressing 5-LO and AKT/GSK3β Signaling

2021-06-15

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<title>Abstract</title> <p><bold>Background</bold>Osteoclast excessive activation was closely related to bone diseases such as osteoporosis and rheumatoid arthritis. Sec-O-glucosylhamaudol (SOG), an active flavonoid compound derived from the root of divaricate <italic>Saposhnikovia</italic>, was reported to exhibit analgesic, anti-inflammatory and high 5-lipoxygenase (5-LO) inhibitory effects. However, its effect...

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Literature Corpus work
41bd2ec1-834e-5a3e-88e2-cefb70ae2893
DOI
10.21203/rs.3.rs-582692/v1
Open publication

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Sec-O-glucosylhamaudol Inhibits RANKL-induced Osteoclastogenesis Via Repressing 5-LO and AKT/GSK3β SignalingDOI 10.21203/rs.3.rs-582692/v1
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