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Article

Possible mechanisms of prednisolone-induced osteoporosis in zebrafish larva.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 May 2018

He Hanliang, Wang Chunqing, Tang Qifeng, Yang Fan, Xu Youjia

Abstract excerpt

Glucocorticoid-induced osteoporosis (GIOP) is a serious clinical bone disease that results from the long-term consumption of glucocorticoids or glucocorticoid-like drugs. Although many studies have attempted to determine the mechanisms of GIOP, they are still unclear. In this study, we established a zebrafish model of glucocorticoid-like drug-induced osteoporosis by treating larvae with prednisolone. We then...

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Identifiers

PMID: 29635908
DOI: 10.1016/j.biopha.2018.02.082

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