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Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high-dosage of dexamethasone

2020-10-20

Abstract excerpt

<h4>Background: </h4> Abnormalities in apoptosis, cell cycle, proliferation, and differentiation of human bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and remodeling, and resulting in various skeletal disorders. Long-term exposure to a high dosage of dexamethasone (Dex) induces apoptosis and inhibits the proliferation of mesenchymal stromal cells (MSCs), which are probable prima...

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Literature Corpus work
57d9eda6-a2c4-5a77-9d05-b2705a8b97cd
DOI
10.21203/rs.3.rs-34807/v2
Open publication

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Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high-dosage of dexamethasoneDOI 10.21203/rs.3.rs-34807/v2
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