Article

Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity

2023-03-16

Abstract excerpt

Cancer represents a broad spectrum of molecularly and morphologically diverse diseases. Individuals with the same clinical diagnosis can have tumors with drastically different molecular profiles and clinical response to treatment. It remains unclear when these differences arise during disease course and why some tumors are addicted to one oncogenic pathway over another. Somatic genomic aberrations occur within the...

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Literature Corpus work: e23a5728-4275-5c9f-b3ca-6f419331d329
DOI: 10.1101/2023.03.15.532870

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