Article
Immuno-oncology from the perspective of somatic evolution.
Seminars in cancer biology - 1 Oct 2018
González Santiago, Volkova Nadezda, Beer Philip, Gerstung Moritz
Abstract excerpt
The past years have witnessed significant success for cancer immunotherapies that activate a patient's immune system against their cancer cells. At the same time our understanding of the genetic changes driving tumor evolution have progressed dramatically. The study of cancer genomes has shown that tumors are best understood as cell populations governed by the rules of evolution, leading to the emergence and...
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