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Article

Immune evasion impacts the landscape of driver genes during cancer evolution.

Genome biology - 26 Jun 2024

Gourmet Lucie, Sottoriva Andrea, Walker-Samuel Simon, Secrier Maria, Zapata Luis

Abstract excerpt

BACKGROUND: Carcinogenesis is driven by interactions between genetic mutations and the local tumor microenvironment. Recent research has identified hundreds of cancer driver genes; however, these studies often include a mixture of different molecular subtypes and ecological niches and ignore the impact of the immune system. RESULTS: In this study, we compare the landscape of driver genes in tumors that escaped...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38926878
DOI: 10.1186/s13059-024-03302-x
PMCID: PMC11210199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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