Article

Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity

2025-08-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Knowledge gaps include whether molecular endotypes of psoriasis underlie distinct clinical phenotypes and the positive and negative molecular regulators of disease severity across tissue compartments. <h4>Methods</h4> We performe...

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Literature Corpus work: e1e7fada-05af-5d2c-aa25-5a7eabff2d79
DOI: 10.1101/2025.07.29.666780

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