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Article

Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin

2022-10-17

Abstract excerpt

<h4>Background</h4> Psoriasis is a chronic, systemic inflammatory condition, primarily affecting skin and joints. It is an immune-mediated disease driven by IL-17-producing T cells in the skin. However, epidermal cells such as keratinocytes are now also recognized as essential contributors to pathogenesis. We hypothesized that, under immunosuppressive treatment, skin inflammation alters the effect of genetic varia...

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Identifiers and source

Literature Corpus work
c290668c-9a31-5ae0-ab1d-1a04b4427538
DOI
10.1101/2022.10.14.22281091
Open publication

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Immunosuppression causes dynamic changes in expression QTLs in psoriatic skinDOI 10.1101/2022.10.14.22281091
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