Article
Genetic liability to psoriasis predicts severe disease outcomes.
Genome medicine - 17 Dec 2025
Saklatvala Jake R, Lessard Samuel, Teder-Laving Maris, Thomas Laurent F, Ramessur Ravi, Zierer Jonas, Åsvold Bjørn Olav, Barton Anne, Baudry David, Bowes John, Brumpton Ben, Bruno Sandro, Chandran Vinod, Chatelain Clément, de Rinaldis Emanuele, Elder James T, Ellinghaus David, Foerster John, Franke Andre, Gladman Dafna D, Gulliver Wayne, Hüffmeier Ulrike, Huilaja Laura, Hveem Kristian, Khader Shameer, Kingo Külli, Klinger Katherine, Kolbinger Frank, Kõks Sulev, Liao Wilson, Nair Rajan P, Nititham Joanne, Rahman Proton, Reis André, Sagoo Manpreet K, Stuart Philip E, Tasanen Kaisa, Traks Tanel, Tsoi Lam C, Uebe Steffen, Watts Katie, Barker Jonathan N, Mahil Satveer K, Langan Sinéad M, Brown Sara J, Løset Mari, Paternoster Lavinia, Dand Nick, Smith Catherine H, Simpson Michael A
Abstract excerpt
BACKGROUND: Psoriasis is a common inflammatory skin disease with heterogeneous presentation. Up to 30% of individuals have severe disease with a greater surface area of skin involvement, co-morbidity burden and impact on quality of life. Prognostic biomarkers of psoriasis severity could improve allocation of clinical resources and enable earlier intervention to prevent disease progression, and a genetic biomarker...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.