Article

A priority index-based computational medicine framework (PimRNA) for prioritising personalised mRNA cancer vaccines

2026-05-29

Abstract excerpt

<h4>Background</h4> The development of personalised mRNA cancer vaccines holds considerable promise for oncology, yet a significant translational gap persists between neoantigen identification and the selection of therapeutically impactful targets. Current approaches predominantly prioritise human leukocyte antigen (HLA) binding affinity and immunogenicity, often overlooking the systems-level biological context o...

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Literature Corpus work: e1b16d45-2ea1-523c-8e27-cc15abe3ad10
DOI: 10.64898/2026.05.26.26354114

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