Article

Beyond MHC binding: immunogenicity prediction tools to refine neoantigen selection in cancer patients

2023-04-25

Abstract excerpt

In the last years, multiple efforts have been made to accurately predict neoantigens derived from somatic mutations in cancer patients, either to develop personalized therapeutic vaccines or to study immune responses after cancer immunotherapy. In this context, the increasing accessibility of paired whole-exome sequencing (WES) of tumor biopsies and matched normal tissue as well as RNA sequencing (RNA-Seq) has pro...

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Literature Corpus work: cea484e1-b391-5c56-917c-98dd168c5090
DOI: 10.37349/ei.2023.00091

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