Article

Prioritizing candidate peptides for cancer vaccines by PEPPRMINT: a statistical model to predict peptide presentation by HLA-I proteins

2021-09-26

Abstract excerpt

Recent development of cancer immunotherapy has opened unprecedented avenues to eliminate tumor cells using the human immune system. Cancer vaccines composed of neoantigens, or peptides unique to tumor cells due to somatic mutations, have emerged as a promising approach to activate or strengthen the immune response against cancer. A key step to identifying neoantigens is computationally predicting which somatically...

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Literature Corpus work: e185ae42-265c-5544-98d6-a31f50acfbfe
DOI: 10.1101/2021.09.24.461596

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