Article

NeoScore integrates characteristics of the neoantigen:MHC class I interaction and expression to accurately prioritize immunogenic neoantigens

2021-06-27

Abstract excerpt

Accurate prioritization of immunogenic neoantigens is key to developing personalized cancer vaccines and distinguishing those patients likely to respond to immune checkpoint inhibition. However, there is no consensus regarding which characteristics best predict neoantigen immunogenicity, and no model to date has both high sensitivity and specificity and a significant association with survival in response to immuno...

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Literature Corpus work: 806b0b59-41b9-5851-88ac-28fdfae6f7dc
DOI: 10.1101/2021.06.24.21259393

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