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Article

Shared Genetic Underpinnings of Gray Matter Volume Alterations and Metabolic Traits in Major Depressive Disorder

2025-12-01

Abstract excerpt

<title>Abstract</title> <p> Background Major depressive disorder (MDD) is linked to extensive gray matter volume (GMV) reductions and frequently co-occurs with metabolic dysfunction. However, the shared genetic basis linking neurostructural abnormalities and metabolic traits remains poorly understood. Methods Using a coordinate-based meta-analytic framework, we synthesized findings from 57 voxel-based morphometr...

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Literature Corpus work
e0974668-7d88-5bed-a4ff-fc2465cca8ff
DOI
10.21203/rs.3.rs-7971333/v1
Open publication

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Shared Genetic Underpinnings of Gray Matter Volume Alterations and Metabolic Traits in Major Depressive DisorderDOI 10.21203/rs.3.rs-7971333/v1
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