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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder

2017-07-24

Abstract excerpt

Major depressive disorder (MDD) is a notably complex illness with a lifetime prevalence of 14%. 1 It is often chronic or recurrent and is thus accompanied by considerable morbidity, excess mortality, substantial costs, and heightened risk of suicide. 2-7 MDD is a major cause of disability worldwide. 8 We conducted a genome-wide association (GWA) meta-analysis in 130,664 MDD cases and 330,470 controls, and ident...

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Literature Corpus work
92e9bcda-7511-51e8-9e87-0de3bf1fdf1b
DOI
10.1101/167577
Open publication

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorderDOI 10.1101/167577
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