Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder

5 Feb 2019

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) is a leading cause of disability worldwide and influenced by both environmental and genetic factors. Genetic studies of MDD have focused on common variants and have been constrained by the heterogeneity of clinical symptoms. METHODS: We sequenced the exome of 77 cases and 245 controls of Han Chinese ancestry and scanned their brain. Burden tests of rare variants were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Functional Brain Connectivity Studies
Share to Genetic Associations and Epidemiology
Share to Treatment of Major Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30722798
DOI: 10.1017/s0033291719000072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A joint study of whole exome sequencing and structural MRI analysis in major depressive disorderPMID 30722798Read ↗

Integration of Whole-Exome Sequencing and Structural Neuroimaging Analysis in Major Depressive Disorder: A Joint StudySemantic proximity Read ↗

ENIGMA MDD: Seven Years of Global Neuroimaging Studies of Major Depression through Worldwide Data SharingSemantic proximity Read ↗

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorderSemantic proximity Read ↗

Shared Genetic Underpinnings of Gray Matter Volume Alterations and Metabolic Traits in Major Depressive DisorderSemantic proximity Read ↗

Identification of 64 new risk loci for major depression, refinement of the genetic architecture and risk prediction of recurrence and comorbiditiesSemantic proximity Read ↗

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.Semantic proximity Read ↗

Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies.Semantic proximity Read ↗

Exome-wide screening identifies novel rare risk variants for major depression disorder.Semantic proximity Read ↗

The Genetic Architecture of Major Depressive Disorder in Han Chinese Women.Semantic proximity Read ↗

The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.Semantic proximity Read ↗

Symptom-specific genetics reveal heterogeneity within major depressive disorderSemantic proximity Read ↗

The genetic basis of major depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.