Article

Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

2020-10-28

Abstract excerpt

<h4>ABSTRACT</h4> Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression, and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays an integral role in regulating vascular barrier function physiologically and in pathologies, such as cancer, ischemic stroke, cardiovascular disease, retinal con...

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Literature Corpus work: e0837a50-5f54-5049-af97-69eaff20e4a5
DOI: 10.1101/2020.10.27.358374

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