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Article

Vegf signaling promotes vascular endothelial differentiation by modulating etv2 expression.

Developmental biology - 15 Apr 2017

Casie Chetty Satish, Rost Megan S, Enriquez Jacob Ryan, Schumacher Jennifer A, Baltrunaite Kristina, Rossi Andrea, Stainier Didier Y R, Sumanas Saulius

Abstract excerpt

Vasculogenesis involves the differentiation of vascular endothelial progenitors de novo from undifferentiated mesoderm, their migration and coalescence to form the major embryonic vessels and the acquisition of arterial or venous identity. Vascular Endothelial Growth Factor (Vegf) signaling plays multiple roles during vascular development. However, its function during embryonic vasculogenesis has been...

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PMID: 28279709
DOI: 10.1016/j.ydbio.2017.03.005
PMCID: PMC5419721

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