Article

Applying the auxin-inducible degradation (AID) system for rapid protein depletion in mammalian cells

2017-08-31

Abstract excerpt

The ability to deplete a protein of interest is critical for dissecting cellular processes. Traditional methods of protein depletion are often slow-acting, which can be problematic when characterizing a cellular process that occurs within a short period of time. Furthermore, these methods are usually not reversible. Recent advances to achieve protein depletion function by inducibly trafficking proteins of interest...

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Literature Corpus work: e04e047f-dd24-5d01-9552-14d6f56f569d
DOI: 10.1101/182840

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