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Expanding the <i>Caenorhabditis elegans</i> auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editing

2020-05-13

Abstract excerpt

The auxin-inducible degron (AID) system has emerged as a powerful tool to conditionally deplete proteins in a range of organisms and cell-types. Here, we describe a toolkit to augment the use of the AID system in Caenorhabditis elegans . We have generated a set of single-copy, tissue-specific (germline, intestine, neuron, muscle, hypodermis, seam cell, anchor cell) and pan-somatic TIR1- expressing strains carryi...

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Identifiers and source

Literature Corpus work
951df671-46c1-5743-a9a1-a9ddd054cbdc
DOI
10.1101/2020.05.12.090217
Open publication

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Expanding the <i>Caenorhabditis elegans</i> auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editingDOI 10.1101/2020.05.12.090217
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