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Fluoxetine-induced neurogenesis and chronic antidepressant effects requires the dopamine D2 receptor

2026-03-31

Abstract excerpt

Major depressive disorder (MDD) is a common psychiatric illness with a high proportion of patients being nonresponsive to therapy. Selective serotonin reuptake inhibitors (SSRI) are widely prescribed for treating depression. Chronic SSRI administration is needed for therapeutic effects, a process implicating in part, increased neurogenesis in the hippocampus. Recent genome wide association studies (GWAS) identifie...

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Literature Corpus work
e01fb954-a1f6-55a8-8a34-caeeaec6183c
DOI
10.64898/2026.03.29.715084
Open publication

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Fluoxetine-induced neurogenesis and chronic antidepressant effects requires the dopamine D2 receptorDOI 10.64898/2026.03.29.715084
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