Article

The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer

2023-09-17

Abstract excerpt

<h4>ABSTRACT</h4> A tumor cell subpopulation of tumor-initiating cells (TIC), or “cancer stem cells”, are associated with therapeutic resistance, as well as both local and distant recurrence. Enriched populations of TIC are identified by markers including aldehyde dehydrogenase (ALDH1) activity, the cell surface marker combination CD44 + /CD24 − , or fluorescent reporters for signaling pathways that regulate TI...

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Literature Corpus work: dfb7d8b8-f803-593d-b51a-71459e7546dc
DOI: 10.1101/2023.09.15.557958

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