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Article

BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer.

Biochemical and biophysical research communications - 22 Jan 2021

Wang Hexiang, Gao Lin, Qi Mei, Su Peng, Xiong Xueting, Zhao Jian, Hu Jing, Han Bo

Abstract excerpt

Triple-negative breast cancer (TNBC) is a major challenge in clinical practice due to its aggressiveness and lack of targeted treatment. Cancer stem-like traits contribute to tumorigenesis and immune privilege of TNBC. However, the relationship of stemness and immunosurveillance remains unclear. Here, we demonstrate that BTF3 expression is related with stem-like properties in TNBC cells. BTF3 modulates stemness,...

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Source

Identifiers

PMID: 33383560
DOI: 10.1016/j.bbrc.2020.12.060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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