Article

Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B

2021-05-05

Abstract excerpt

<title>Abstract</title> <p>Cancer stem cells (CSCs) are immature, immortal cells within tumors, adept at resisting therapeutic pressure and responsible for local and distant disease recurrence. Non-genetic mechanisms of acquired resistance are increasingly being described, however molecular insights into this evolutionary process still lack. Here, we showed that Type I interferons (IFNs-I) act as molecular hubs o...

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Literature Corpus work: a3c5fded-5aa0-5d90-b0f0-bd56822c3a5f
DOI: 10.21203/rs.3.rs-436936/v1

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