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Enhanced activity of glycolytic enzymes in <i>Drosophila</i> and human cell models of Parkinson’s disease based on <i>DJ-1</i> deficiency

2020-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease (PD) is a neurodenerative debilitating disorder characterized by progressive disturbances in motor, autonomic and psychiatric functions. The pathological hallmark of PD is the loss of dopaminergic neurons in the substantia nigra pars compacta, which causes striatal dopamine deficiency. Although most PD cases are sporadic (iPD), approximately 5-10% of all patients suffer from...

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Literature Corpus work
dee340ae-b527-5f8e-b92b-1d208c557a37
DOI
10.1101/2020.03.10.985135
Open publication

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Enhanced activity of glycolytic enzymes in <i>Drosophila</i> and human cell models of Parkinson’s disease based on <i>DJ-1</i> deficiencyDOI 10.1101/2020.03.10.985135
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