Article

Ubp2 modulates DJ-1-mediated redox-dependent mitochondrial dynamics in <i>Saccharomyces cerevisiae</i>

2024-06-29

Abstract excerpt

Mitochondrial integrity is a crucial determinant of overall cellular health. Mitochondrial dysfunction and impediments in regulating organellar homeostasis contribute majorly to the pathophysiological manifestation of several neurological disorders. Mutations in human DJ-1 ( PARK7 ) have been implicated in the deregulation of mitochondrial homeostasis, a critical cellular etiology observed in Parkinson’s disease...

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Literature Corpus work: 5da81b57-a696-5a3c-ae8b-cb9a1eef1d2f
DOI: 10.1101/2024.06.28.601193

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