Article

Inferring Multi-Stage Pathway Progression Models from Tumor Phylogenies

2026-05-28

Abstract excerpt

Cancer progression is an evolutionary process driven by the accumulation and selection of somatic mutations, giving rise to genetically diverse subclonal populations within tumors. Understanding the dependencies among mutations and identifying recurrent evolutionary trajectories is critical for understanding cancer progression and informing therapeutic strategies. Recent advances in genomic sequencing and phylogen...

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Literature Corpus work: a289d7e2-9bf8-5ac0-bc1f-9747e4aa9db4
DOI: 10.64898/2026.05.25.727519

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