Article

Transcriptomic entropy reveals tissue-specific patterns in aging and predicts cancer progression

2025-07-04

Abstract excerpt

<h4> ABSTRACT </h4> Aging and cancer share complex molecular mechanisms, yet distinguishing between causative factors and byproducts remains challenging. Here, we investigated the role of transcriptomic entropy in aging and cancer processes by analyzing RNA-sequencing data from thousands of human and mouse samples. We found that entropy changes during aging are highly tissue-specific, with some tissues showing i...

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Literature Corpus work: ddc261ce-2fd5-5a93-83a0-d636ea71cf8b
DOI: 10.1101/2025.06.29.662218

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