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Article

Entropy measures quantify global splicing disorders in cancer.

PLoS computational biology - 14 Mar 2008

Ritchie William, Granjeaud Samuel, Puthier Denis, Gautheret Daniel

Abstract excerpt

Most mammalian genes are able to express several splice variants in a phenomenon known as alternative splicing. Serious alterations of alternative splicing occur in cancer tissues, leading to expression of multiple aberrant splice forms. Most studies of alternative splicing defects have focused on the identification of cancer-specific splice variants as potential therapeutic targets. Here, we examine instead the...

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Identifiers

PMID: 18369415
DOI: 10.1371/journal.pcbi.1000011
PMCID: PMC2268240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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