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Single-Cell Transcriptomics Reveals the Expression of Aging- and Senescence-Associated Genes in Distinct Cancer Cell Populations

11 Nov 2021

Abstract excerpt

The human aging process is associated with molecular changes and cellular degeneration, resulting in a significant increase in cancer incidence with age. Despite their potential correlation, the relationship between cancer- and ageing-related transcriptional changes is largely unknown. In this study, we aimed to analyze aging-associated transcriptional patterns in publicly available bulk mRNA-seq and single-cell...

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Share to Epigenetics and DNA Methylation
Share to Single-cell and spatial transcriptomics
Share to Telomeres, Telomerase, and Senescence

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PMID: 34831349
DOI: 10.3390/cells10113126

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