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KLIFS: an overhaul after the first 5 years of supporting kinase research

30 Sept 2020

Abstract excerpt

Kinases are a prime target of drug development efforts with >60 drug approvals in the past two decades. Due to the research into this protein family, a wealth of data has been accumulated that keeps on growing. KLIFS-Kinase-Ligand Interaction Fingerprints and Structures-is a structural database focusing on how kinase inhibitors interact with their targets. The aim of KLIFS is to support (structure-based) kinase...

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PMID: 33084889
DOI: 10.1093/nar/gkaa895

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