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Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

23 Jul 2020

Abstract excerpt

Protein kinases are essential for signal transduction and control of most cellular processes, including metabolism, membrane transport, motility, and cell cycle. Despite the critical role of kinases in cells and their strong association with diseases, good coverage of their interactions is available for only a fraction of the 535 human kinases. Here, we present a comprehensive mass-spectrometry-based analysis of...

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PMID: 32707033
DOI: 10.1016/j.molcel.2020.07.001

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