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Targeted downregulation of estradiol binding Na + /H + exchanger nhx-2, mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in C. elegans

2020-07-30

Abstract excerpt

Setting in of reproductive senescence (RS) gives rise to several changes, making aged individuals susceptible to multiple disorders including neurodegenerative diseases, cardiovascular ailments and bone disorders amongst others. The present study, employing transgenic C. elegans that expresses ‘human’ alpha synuclein, endeavors to decipher the association of reproductive senescence with age-associated neurodegene...

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Literature Corpus work: dce63cc5-0910-5eaf-8faa-8095f9df69a2
DOI: 10.1101/2020.07.30.229344

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Targeted downregulation of estradiol binding Na + /H + exchanger nhx-2, mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in C. elegansDOI 10.1101/2020.07.30.229344Read

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Targeted downregulation of estradiol binding Na <sup>+</sup> /H <sup>+</sup> exchanger <i>nhx-2,</i> mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in <i>C. elegans</i>

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