Article

A dicer-related helicase opposes the age-related pathology from SKN-1 activation in ASI neurons

2023-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Coordination of cellular responses to stress are essential for health across the lifespan. The transcription factor SKN-1 is an essential homeostat that mediates survival in stress-inducing environments and cellular dysfunction, but constitutive activation of SKN-1 drives premature aging thus revealing the importance of turning off cytoprotective pathways. Here we identify how SKN-1 activation i...

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Literature Corpus work: 1e44e109-adcb-5847-a722-3cb0e7a88730
DOI: 10.1101/2023.10.01.560409

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