Article

Opposing steroid signals modulate protein homeostasis through deep changes in fat metabolism in <i>Caenorhabditis elegans</i>

2019-02-15

Abstract excerpt

<h4>ABSTRACT</h4> Protein homeostasis is crucial for viability of all organisms, and mutations that enhance protein aggregation cause different human pathologies, including polyglutamine (polyQ) diseases, such as some spinocerebellar ataxias or Huntington disease. Here, we report that neuronal Stomatin-like protein UNC-1 protects against aggregation of prone-to-aggregate proteins, like polyQs, α-synuclein and β-a...

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Literature Corpus work: b65d9a1c-a11f-5823-bbfc-a34d955aadb0
DOI: 10.1101/551580

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