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Article

Sir-2.1 modulates ‘calorie-restriction-mediated’ prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson’s disease

30 Aug 2011

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Identifiers

PMID: 21889494
DOI: 10.1016/j.bbrc.2011.08.092

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Sir-2.1 modulates ‘calorie-restriction-mediated’ prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson’s diseasePMID 21889494Read ↗

Sir2 mediates longevity in the fly through a pathway related to calorie restriction.Semantic proximity Read ↗

Dietary restriction involves <scp>NAD</scp><sup>+</sup>‐dependent mechanisms and a shift toward oxidative metabolismSemantic proximity Read ↗

The role of calorie restriction and SIRT1 in prion-mediated neurodegenerationSemantic proximity Read ↗

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Systematic Review of Caenorhabditis elegans Models for Mechanism Research and Drug Discovery in Parkinson’s DiseaseSemantic proximity Read ↗

Molecular Links between Caloric Restriction and Sir2/SIRT1 ActivationSemantic proximity Read ↗

Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans.Semantic proximity Read ↗

Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1Semantic proximity Read ↗

Optimizing Dietary Restriction for Genetic Epistasis Analysis and Gene Discovery in C. elegansSemantic proximity Read ↗

Caloric restriction and the precision-control of autophagy: A strategy for delaying neurodegenerative disease progressionSemantic proximity Read ↗

Modelling Parkinson's Disease in C. elegans : Strengths and LimitationsSemantic proximity Read ↗

Targeted downregulation of estradiol binding Na <sup>+</sup> /H <sup>+</sup> exchanger <i>nhx-2,</i> mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in <i>C. elegans</i>Semantic proximity Read ↗

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