Article

NHR-49 Acts in Distinct Tissues to Promote Longevity versus Innate Immunity

2020-09-11

Abstract excerpt

<h4>ABSTRACT</h4> Aging and immunity are inextricably linked and many genes that extend lifespan also enhance immunoresistance. However, it remains unclear if longevity-enhancing factors modulate immunity and longevity by distinct or shared mechanisms. Here, we demonstrate that the Caenorhabditis elegans pro-longevity factor, NHR-49, also promotes resistance against Pseudomonas aeruginosa , but modulates immuni...

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Literature Corpus work: 4d52d69c-36d4-57c3-bfba-0bb765fa59bf
DOI: 10.1101/2020.09.11.290452

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